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Each uncoated tablet contains :
Composition:
Thyroxine Sodium IP
equlvalent to anhydrous Thyroxine Sodium IP.........100
mcg
(Synthetic Thyroid Hormones)
Colour : Quinoline Yellow WS
Indications:
Hypothyroidism, Cretinism, non-toxic goitre, myxoedema,
coma.
Description:
Thyroid
hormone drugs are natural or synthetic preparations
containing tetraiodothyronine (T4,
levothyroxine) sodium or triiodothyronine (T3,
liothyronine) sodium or both. T4
and T3 are produced in the
human thyroid gland by the iodination and coupling of
the amino acid tyrosine. T4
contains four iodine atoms and is formed by the coupling
of two molecules of diiodotyrosine (DIT). T3
contains three atoms of iodine and is formed by the
coupling of one molecule of DIT with one molecule of
monoiodotyrosine (MIT). Both hormones are stored in the
thyroid colloid as thyroglobulin and released into the
circulation. The major source of T3
has been shown to be peripheral deiodination of T4.
T3 is bound less firmly than T4
in the serum, enters peripheral tissues more readily,
and binds to specific nuclear receptor(s) to initiate
hormonal, metabolic effects. T4
is the prohormone which is deiodinated to T3
for hormone activity.
Contraindications
Thyroid
hormone preparations are generally contraindicated in
patients with diagnosed but as yet uncorrected adrenal
cortical insufficiency or untreated thyrotoxicosis.
Thyroid hormone preparations are also generally
contraindicated in patients with hypersensitivity to any
of the active or extraneous constituents of these
preparations; however, there is no well-documented
evidence in the literature of true allergic or
idiosyncratic reactions to thyroid hormone.
Dosage:
As per the physician’s advice.
Presentations:
100 tablets
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Stockiest
99.00 79.20
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