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Therapeutic Index

PAIN RELIEF
Each film-coated tablet contains:

Composition:
Paracetamol I.P................................................325 mg
Ibuprofen I.P......................................................200 mg
Caffeine I.P..........................................................40 mg
Excipients..................................................................q.s.

Indications:
For fast relief from Headache, Toothache, Muscular ache, pain, Cold Symptoms and Feverish conditions.

Description:
Paracetamol (called acetaminophen in the USA) is a derivative of p-aminophenol, which corresponds to the active principal metabolite phenacetin.
Its mechanism of action is not clearly established. It appears that paracetamol inhibits prostaglandin biosynthesis in the central nervous system but not (or hardly) in the peripheral tissues. In any case, paracetamol only has minimal anti-inflammatory action compared to non-steroidal anti-inflammatory agents.

Contraindications
Paracetamol should not be used in hypersensitivity to the preparation and in severe liver diseases.

Special warnings and precautions
The preparation should be used with care in patients with liver and renal diseases. The treatment with Paracetamol may change the laboratory tests of uric acid and blood glucose analysis. In severe renal failure the interval between two consecutive takings should not be shorter than 8 hours. The treatment with the preparation is not advisable during the first trimester of the pregnancy. In nursing women the preparation should be used with strictly observation of the therapeutic dose and duration of the treatment.

Dosage:  1-2 Tablets 3 t o 4 times daily. In accordance with age or as directed by the Physician.

Presentations:    10 tablets             

                                     MRP             Retailer           Stockiest
                                    
18.00              14.40                 12.96

 
 

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