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Therapeutic Index

CETRILIN-A

Each tablet contains:

Composition:
LevoCetirizine Dihydrochloride......................................5 mg
Pseudoephedrine...........................................................30 mg
Ambroxol...........................................................................60 mg

Indications :
Cetrilin-A is indicated in the treatment of perennial and seasonal allergic rhinitis pruritus, allergic asthma, allergic conjunctivitis and urticaria.

Description:
An antihistamine is a drug serves to reduce or eliminate effects. which serves to reduce or eliminate effects mediated by histamine. an endogenous chemical mediator released during allergic reactions. Only agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines - other agents may have antihistaminergic action but are not true antihistamines.In common use, the term antihistamine refers only to H1-receptor antagonists, also known as H1-antihistamines.
Ambroxol (group of benzilamides) belongs to secretolitical and secretomotoric medicinal products. It possesses expressed expectorant effect. Mechanism of action of the medicinal product is stipulated by stimulation of serous cells of tonsils of bronchial tubes' mucous membrane, increasing of mucous secretion content and changing of correlation of serous and mucous components of phlegm, breached under pathological processes in lungs. Under this hydrolyzing ferments activate and releasing of lizosoms from Clark's cells strengthens, that causes decreasing of viscosity of phlegm. Ambroxol increases content of surphactant in lungs, that is dealt with strengthening of synthesis of the last and secretion in alveolar pneumocytes, and also with breach of its disintegration. The medicinal product increases mucociliar transport of phlegm. It suppresses coughing insignificantly.
Ambroxol well penetrates through the placenta barrier, improving synthesis of surphactants during uterine life of foetus, and also it has an ability to warn syndrome of insufficient breathing in newborn. The medicinal product does not cause immense creating of saecretion, reduces spastic hyperactivity of bronchial tubes - one of the main factors of developing of bronchial asthma under allergy. Ambroxol is more effective, than its predecessor - bromhexin, it is non-toxic one and well endured by patients. Action of retard form of ambroxol is kept in 9 - 10 hours after administration inside.

Side effects:
Under individual hypersensitivity to ambroxol allergic reactions such as skin rash, nettle-rash, angioneurotic oedema are possible. Under the prolonged administration in large doses pain in epigastrial area, nausea, vomiting can appear.

Contraindications: It is necessary to be careful under hypersensitivity to ambroxol. It is not administrated during the first term of pregnancy, lactation period, under ulcer disease of stomach and duodenum, spasmodic states of any etiology.

Dosage : As per the physicianís advice

Presentations :  10 tablets                                
                                   MRP               Retailer             Stockist
                                  34.73                27.78                  25.00

 
 

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