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Therapeutic Index

Each capsule (E.C. granules ) contains:


Omeprazol..................................................................20 mg



Ulcer, duodenal; Adenoma, multiple endocrine; Esophagitis, erosive; Gastroesophageal Reflux Disease; Mastocytosis, systemic; Ulcer, gastric; Zollinger-Ellison syndrome; Pregnancy Category C;



Omeprazole is a selective and irreversible proton pump inhibitor. Omeprazole suppresses gastric acid secretion by specific inhibition of the hydrogen–potassium adenosinetriphosphatase (H +, K +-ATPase) enzyme system found at the secretory surface of parietal cells. It inhibits the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen. Since the H +, K +-ATPase enzyme system is regarded as the acid (proton) pump of the gastric mucosa, omeprazole is known as a gastric acid pump inhibitor. The inhibitory effect is dose-related. Omeprazole inhibits both basal and stimulated acid secretion irrespective of the stimulus.


Side/Adverse Effects

Note: Gastric fundic gland polyps have occurred rarely in patients receiving omeprazole; these appear to be benign and reversible upon discontinuance of omeprazole.
Gastroduodenal carcinoids have been reported in patients with Zollinger-Ellison syndrome who have received long-term omeprazole therapy. These carcinoids are believed to be a manifestation of the underlying syndrome, which is known to be associated with such tumors.
Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patient receiving long-term omeprazole therapy.
Overt liver disease has occurred rarely, and included hepatocellular, cholestatic, or mixed hepatitis, liver necrosis (sometimes fatal), hepatic failure (sometimes fatal), and hepatic encephalopathy.
The following side/adverse effects have been selected on the basis of their potential clinical significance (possible signs and symptoms in parentheses where appropriate)—not necessarily inclusive:


Omeprazole delayed-release capsules are contraindicated in patients with known hypersensitivity to any component of the formulation

Dosage: As per the physician’s advice.

Presentations:  10 caps       
                                 MRP           Retailer        Stockiest
9.80               7.84                7.05





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