|
Each uncoated tablet contains :
Composition:
Thyroxine Sodium IP
equlvalent to anhydrous Thyroxine Sodium
IP.........100 mcg
(Synthetic Thyroid Hormones)
Colour : Quinoline Yellow WS
Indications:
Hypothyroidism, Cretinism, non-toxic
goitre, myxoedema, coma.
Description:
Thyroid hormone drugs are natural or
synthetic preparations containing
tetraiodothyronine (T4,
levothyroxine) sodium or
triiodothyronine (T3,
liothyronine) sodium or both. T4
and T3 are
produced in the human thyroid gland by
the iodination and coupling of the amino
acid tyrosine. T4
contains four iodine atoms and is formed
by the coupling of two molecules of
diiodotyrosine (DIT). T3
contains three atoms of iodine and is
formed by the coupling of one molecule
of DIT with one molecule of
monoiodotyrosine (MIT). Both hormones
are stored in the thyroid colloid as
thyroglobulin and released into the
circulation. The major source of T3
has been shown to be peripheral
deiodination of T4.
T3 is bound
less firmly than T4
in the serum, enters peripheral tissues
more readily, and binds to specific
nuclear receptor(s) to initiate
hormonal, metabolic effects. T4
is the prohormone which is deiodinated
to T3 for
hormone activity.
Contraindications
Thyroid hormone preparations are
generally contraindicated in patients
with diagnosed but as yet uncorrected
adrenal cortical insufficiency or
untreated thyrotoxicosis. Thyroid
hormone preparations are also generally
contraindicated in patients with
hypersensitivity to any of the active or
extraneous constituents of these
preparations; however, there is no
well-documented evidence in the
literature of true allergic or
idiosyncratic reactions to thyroid
hormone.
Dosage:
As per the physician’s advice.
Presentations:
100 tablets
MRP Retailer Stockiest
99.00 79.20 71.28
|
Taj Brands
