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Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs or NAIDs, are drugs with analgesic, antipyretic (lowering an elevated body temperature and relieving pain without impairing consciousness) and, in higher doses, with anti-inflammatory effects (reducing inflammation).The most prominent members of this group of drugs are aspirin, ibuprofen, and naproxen partly because they are available over-the-counter in many areas.

Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs or NAIDs, are drugs with analgesic, antipyretic (lowering an elevated body temperature and relieving pain without impairing consciousness) and, in higher doses, with anti-inflammatory effects (reducing inflammation).The most prominent members of this group of drugs are aspirin, ibuprofen, and naproxen partly because they are available over-the-counter in many areas.

Uses
NSAIDs are generally indicated for the symptomatic relief of the following conditions:

* Rheumatoid arthritis
* Osteoarthritis
* Inflammatory arthropathies (e.g. ankylosing spondylitis, psoriatic arthritis, Reiter's syndrome)
* Acute gout
* Dysmenorrhoea (menstrual pain)
* Metastatic bone pain
* Headache and migraine
* Postoperative pain
* Mild-to-moderate pain due to inflammation and tissue injury
* Pyrexia (fever)
* Ileus
* Renal colic
* They are also given to neonate infants whose ductus arteriosus is not closed within 24 hours of birth

Examples

NSAIDs can be broadly classified based on their chemical structure. NSAIDs within a group will tend to have similar characteristics and tolerability. There is little difference in clinical efficacy among the NSAIDs when used at equivalent doses. Rather, differences among compounds tended to be with regards to dosing regimens (related to the compound's elimination half-life), route of administration, and tolerability profile. Some more common examples are given below.

* Celecoxib
* Etoricoxib
* Lumiracoxib
* Parecoxib
* Rofecoxib
* Valdecoxib
*Nimesulide (banned by several countries for the potential risk of hepatotoxicity)

Others

* Ibuprofen
* Naproxen
* Diclofenac
* Licofelone

 
 

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