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    Each Injection contains:


     Pantoprazole ..................................................................40 mg



     Protozole reduces the amount of acid in the stomach and              

     duodenum. This helps to heal peptic ulcers and helps to prevent
 them from recurring. It also helps to relieve the symptoms of

     reflux oesophagitis.



    Proton pump inhibitors act by irreversibly blocking the   

    hydrogen/potassium adenosine triphosphatase enzyme system (    the H+/K+ ATPase, or more commonly just gastric proton pump

     of the gastric parietal cell. The proton pump is the terminal stage

     n gastric acid secretion, being directly responsible for secreting H

    + ions into the gastric lumen, making it an ideal target for


     acid secretion.

    Targeting the terminal-step in acid production, as well as the

     irreversible nature of the inhibition, result in a       class of drugs

   t hat is significantly more effective than H2 antagonists and

     reduces gastric acid secretion by up to 99%.

   The lack of the acid in the stomach will aid in the healing of      

    duodenal ulcers, and reduces the pain from indigestion and

h eartburn, which can be exacerbated by stomach acid. However,  

   lack of stomach acid may also contribute to hypochlorhydria, a la

c k of sufficient hydrochloric acid, or HCl. Hydrochloric acid is r

    equired for absorption of nutrients, particularly calcium.

 The proton pump inhibitors are given in an inactive form. The 

 inactive form is neutrally charged (lipophilic)   and readily crosses

 cell membranes into intracellular compartments (like the parietal

 cell canaliculus) that have acidic environments. In an acid

 environment, the inactive drug is protonated and rearranges into

 its active form. As described above, the active form will covalently

 and irreversibly bind to the gastric proton pump, deactivating it.

osage: As per the physician’s advice.


     Presentation:         MRP      Retailer     Stockiest

                                      52.60       42.08            37.87

Structural Formula


Taj Values



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