|
Each Injection contains:
Composition:
Inj. Ondansetron 2ml
Amp..............................................2mg
/ml
Indications:
Emetron helps to relieve nausea and
vomiting, especially when associated
with the treatment of cancer
(chemotherapy). Ondansetron may also be
used to prevent or treat nausea and
vomiting that occurs after surgery, and
occasionally is used to treat severe
vomiting during pregnancy.
Description:
Ondansetron is a competitive, highly
selective antagonist of
5-hydroxytryptamine (serotonin) subtype
3 (5-HT 3) receptors. 5-HT
3 receptors are present
peripherally on vagal nerve terminals
centrally in the area postrema of the
brain. It is not certain whether
ondansetron's action is mediated
peripherally, centrally, or both.
Cytotoxic drugs and radiation appear to
damage gastrointestinal mucosa, causing
the release of serotonin from the
enterochromaffin cells of the
gastrointestinal tract. Stimulation of
5-HT 3 receptors causes
transmission of sensory signals to the
vomiting center via vagal afferent
fibers to induce vomiting. By binding to
5-HT 3 receptors, ondansetron
blocks vomiting mediated by serotonin
release.
Ondansetron has no dopamine-receptor
antagonist activity.
Dosage :
As per the physician’s advice.
Presentations
: 2 ml
MRP Retailer Stockiest
28.25 22.60 20.34 |
