Taj Group India
  Quality Medicines Diseases Newsroom Feed back Contactus
IT Services
Home >> 
Wipro Infotech
Taj Products
Therapeutic Index
Allopathic Products
Ayurveic & Herbals
Product Index(M.R.P.)
Down Menu

Taj Brands

Therapeutic Index


Each 5 gm contains:


Triclosan, Silica, Special Flavour.

Indications :
Twice Brushing with Dr. Dentist, gently removes tough stain, long lasting mint flavour keeps mouth clean & fresh, no harsh aprasives or bleach.

Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Resistance to triclosan in Escherichia coli is acquired through a missense mutation in the fabI gene that leads to the expression of FabI[G93V]. The specific activity and substrate affinities of FabI[G93V] are similar to FabI. Two different binding assays establish that triclosan dramatically increases the affinity of FabI for NAD+. In contrast, triclosan does not increase the binding of NAD+ to FabI[G93V]. The x-ray crystal structure of the FabI-NAD+-triclosan complex confirms that hydrogen bonds and hydrophobic interactions between triclosan and both the protein and the NAD+ cofactor contribute to the formation of a stable ternary complex, with the drug binding at the enoyl substrate site. These data show that the formation of a noncovalent "bi-substrate" complex accounts for the effectiveness of triclosan as a FabI inhibitor and illustrates that mutations in the FabI active site that interfere with the formation of a stable FabI-NAD+-triclosan ternary complex acquire resistance to the drug.

Dosage : As per the physician’s advice or Dentist Doctor’s advices.

Presentations :   100 gm     
                                  MRP               Retailer             Stockist
                                 50.00                40.00                  36.00

Wallpaper:  Dr Dentist Extreme ® Taj Pharmaceuticals Limited





Product Downloads:-







Structural Formula


Taj Values

Dr Dentist Extreme ® Taj Pharmaceuticals Limited


Copyright © Taj Pharmaceuticals Ltd. | Privacy Policy | Terms & Conditions | Sitemap