Composition
Alfuzin Tablets
Each tablet contains Alfuzosin hydrochloride (extended release) 10mg
 Indication

Alfuzosin® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.

Important Safety Information
Do not take Alfuzosin if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.

Alfuzosin can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how Alfuzosin will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking Alfuzosin in combination with blood pressure medication or nitrates, or erectile dysfunction medication.

If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking Alfuzosin or have previously been treated with an alpha-blocker.

Before taking Alfuzosin, tell your doctor if you have kidney problems.

Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.

BPH and prostate cancer can cause the same symptoms. However, Alfuzosin is not a treatment for prostate cancer.

The most common side effects with Alfuzosin are dizziness, upper respiratory tract infection, headache, and tiredness.


Indications
Alfuzosin is used to treat symptoms of benign prostatic hyperplasia (BPH, enlarged prostate) such as frequent, urgent need to urinate during the day and at night, weak urine stream, and difficulty urinating. Alfuzosin is in a class of medications called alpha-1 blockers. It works by relaxing the muscles in the prostate and bladder neck to allow urine to flow more easily.

Description
Alpha blocker drug ,relax the muscles in the prostrate gland and the neck of the bladder.This allows the urethra to open wider so that urine flows more easily.  

Contraindications
Alfuzosin should be used with caution in patients with severe renal insufficiency, and should not be prescribed to patients with a known history of QT prolongation or to patients who are taking medications known to prolong the QT interval (term related to cardiology). Alfuzosin should not be used in patients with moderate or severe hepatic insufficiency, (Childs-Pugh categories B and C) since alfuzosin blood levels are increased in these patients. Alfuzosin should not be co-administered with potent CYP3A4 inhibitors such as ketoconazole, itraconazole, and ritonavir, since alfuzosin blood levels are increased. Alfuzosin is contraindicated in patients known to be hypersensitive to alfuzosin hydrochloride or any component of Alfuzosin tablets.
During cataract surgery, a variant of small pupil syndrome known as
Intraoperative Floppy Iris Syndrome (IFIS) has been reported in some patients on
or previously treated with alpha-1 blockers.

OVERDOSAGE

Should overdose of ALFUSIN lead to hypotension, support of the cardiovascular
system is of first importance. Restoration of blood pressure and normalization of
heart rate may be accomplished by keeping the patient in the supine position. If
this measure is inadequate, then the administration of intravenous fluids should
be considered. If necessary, vasopressors should then be used and the renal
function should be monitored and supported as needed. Alfuzosin is 82% to 90%
protein-bound; therefore, dialysis may not be of benefit.

Side effects
The most common side effects are dizziness (due to postural hypotension), upper respiratory tract infection, headache, and fatigue.

Presentation:      10 tablets  
                                  MRP            Retailer           Stockiest
                                 79.50              63.60                  57.24

Alfuzin     Blister pack of 10 capsules